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By binding copper(II) ions, it helps regulate gene expression linked to collagen formation, angiogenesis, antioxidant defense, and tissue remodeling. The peptides small size allows it to penetrate tissues efficiently, and its copper-transfer activity underlies its reported effects on skin, hair, and wound-healing processes in laboratory models

A Phase I safety study and a Phase II ulcerative colitis trial of the BPC-157 formulation PL 14736 were conducted by the Croatian pharmaceutical company Pliva, but full peer-reviewed Phase II efficacy results have not been published

Glutathione supplementation is generally very well tolerated

10.1038/nrclinonc.2017.40 Nat

It is applied in the treatment of a wide range of tumors, most commonly in individual or combined therapies targeting cancers such as skin, breast, head and neck, lung, prostate, and bladder cancers [89]

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