CA-SS-TMR Size:100nmol The Mal-Acetyl group may also

The Mal-Acetyl group may also improve retro-Michael addition stability during antibody conjugation

Product Name Thalidomide-5'-O-C3-OH Synonyms CAS Number 2476318-89-3 Related CAS Molecular Formula C16H16N2O6 Molecular Weight 332

ChemBioChem

Linker substitution influences succinimide ring hydrolysis equilibrium impacting the stability of attachment to antibody-drug conjugates

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

CA-SS-TMR Size:100nmol The Mal-Acetyl group may alsoHaloTag is a self labeling protein tag engineered from the haloalkane dehalogenase DhaA, originally isolated from Rhodococcus rhodochrous. Its active site binds chloroalkane (CA)substrates, forming an irreversible covalent bond. This stable linkage between the HaloTag protein and its ligand enables rapid and efficient isolation and purification of tagged proteins. CA SS TMR is a cleavable HaloTag ligand featuring a disulfide bond that can be cleaved