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112 The Wnt/-catenin signalling pathway is a key downstream molecular pathway of TGF--mediated myocardial fibrosis

In symptomatic Wilson disease the therapeutic goal is to stop progression of liver disease, reversal or improvement of extrahepatic manifestation, and allow an almost normal life expectancy, which in most cases is achievable by the conventional medical therapy (88)

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37 Patients may exhibit clinical features, such as abnormal growth of the hands, feet and facial features, and enlarged organs

10.1007/s12192-015-0654-4 179 TonelliC.ChioI

Its long-acting design extends receptor engagement compared to native amylin