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These findings suggest that TLR4 and RAGE signaling may contribute to distinct stages of dAGEs-induced allergic inflammation: TLR4 drives early barrier disruption and localized inflammation, while RAGE is essential for later-stage immune cell activation and allergen-specific responses

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Results suggest evidence for spatiotemporal variability in ROS frequency and energy fluxes during snowmelt and ROS events in the Northern Hemisphere

Noninvasive in vivo model demonstrating the effects of autonomic innervation on pancreatic islet function

doi: 10.1038/cdd.2013.45 143 LiuYShoji-KawataSSumpterRMJr.WeiYGinetVZhangLet al