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Warsaw: PZWL (2021)

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298 During the early phase of AP, injured acinar cells secrete CXCL8, which contributes to neutrophil activation and recruitment, thereby promoting the downstream inflammatory cascade

Interestingly, NRX can indirectly promote -catenin signaling by modulating Dvl stability

10.3969/j.issn.1008-0805.2017.01.002 85 GrossH.KehrausS.NettM.KnigG

Mitochondrial dysfunction is characterized by various degrees of ultrastructural mitochondrial damage, abnormal morphologic changes, increased permeability of the outer and inner membranes, impaired mitochondrial -oxidation, respiratory chain activity reduction, ROS overproduction, ATP depletion, and oxidative stress-mediated deletions of mtDNA inducing apoptosis (Ramanathan et al