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(PubMed) Durga J, van Boxtel MP, Schouten EG, et al

Growth hormone and cognitive function

Mechanistically, SIRT1 negatively regulates p16 and p21, essential in driving senescence in response to DNA damage

Through Nrf2 activation, these compounds enhance the cells intrinsic defense against oxidative injury in PD models

This makes it particularly susceptible to oxidative stress

Gallic acid is found in various fruits and plant products (such as berries, tea, nuts, and red wine) either in free form or as part of tannins and other polyphenols (32)