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(7) Sarah Wrigley, Donia Arafa, and Daniela Tropea (2017) Insulin-Like Growth Factor 1: At the Crossroads of Brain Development and Aging Frontiets in Cellular Neuroscience, 2017 Feb 1, Volume 11, Page 14

Although rhGH-treatment partly restored reduced expression of GHR and IGF-1 in the kidneys and resulted in profound metabolic effects, including improved weight gain and lower urea serum levels, there was no difference with respect to renal recovery and mortality compared to placebo-treated controls

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