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Early pregnancy can reduce breast cancer incidence, while delayed menopause is linked with breast cancer development ( Nutritional diet Diet may act on different biological mechanisms, such as inflammation, immunity, cell regulation factors, angiogenesis, and growth factors, in the intervention of carcinogenesis ( Molecular mechanisms involved in breast cancer development Carcinogenesis is a complex, multi-step process driven by a variety of molecular and cellular mechanisms ( Figure 2 ) ( Figure 2 In mammary epithelial cells, Bcl-2 is present in non-pregnant women and during early pregnancy, yet it is undetectable during lactation ( The expression of Bcl-2 has been shown to correlate with oestrogen receptor (ER) and progesterone receptor (PR) status in breast cancer