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Single-agent optimization typically outperforms combination protocols in real-world practice

Polyphosphate: a link between platelets, coagulation and inflammation

Within this complex, RAPTOR interacts with the N-terminal region of mTOR, playing a critical role in complex assembly, subcellular localization, stability, and substrates recruitment

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Overall, our results show that a subset of chloroacetamides (including SCLA1, SCLA2 and SCLA3) engages GPX4 to induce ferroptosis in senescent cells