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Description

Modification of human hearing loss by plasma-membrane calcium pump PMCA2

It helps to reduce oxidative stress and maintain immunity

Activated mutations within this pathway represent the most frequent oncogenic factor for many cancers (Khotskaya et al

BMC Bioinformatics 12 , 323 (2011)

The rationale included the possibility of detecting sulfinamides, sulfinic acid and sulfonic acid (-SO 3 H), which, unlike traditional -SNO modifications would be stable during reduction