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Encouragingly, in patients with recurrent platinum-sensitive ovarian cancer, this combination showed significant responses and good tolerability (ORR: 62.2%, mPFS: 11.6 months

Different chemical gradients being established throughout the biofilm community, in combination with limited diffusion and the metabolic activity of resident bacteria, leads to the emergence of distinct subpopulations that often cooperate metabolically but respond differently to the microenvironment depending on their location along the gradient (Penesyan et al., 2020)

Pirooznia et al., 2012)

monocytogenes when lacking the gsh-px gene, together with its adhesion and invasion efficiency, which could be accomplished by binding GSH to PrfA allosterically (Wang et al., 2017)

221,222 These cells have their redox mechanisms to protect themselves from the oxidative by-products of their metabolism

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