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Research has found that carnitine deficiency can cause smooth muscle dysmotility (changes in speed, strength, or coordination) of the gastrointestinal tract (similar to what it does to muscle metabolism, causing muscle weakness), which can cause gastrointestinal discomfort and changes in the microbiota ( gut dysbiosis ), as well as constipation

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NLRP3 is a protein characterized by a nucleotide-binding oligomerization domain (NOD), a leucine-rich repeat (LRR), and a pyrin domain