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Data Availability Data sharing is not applicable to this article as no new data were created or analysed in this study

In this process, tumor cells induce oxidative stress and aerobic glycolysis in neighboring CAFs, forcing them to secrete high-energy metabolites such as lactate and pyruvate

Disruption of gut homeostasis, including alterations in gut microbiota composition, impaired intestinal barrier function and increased microbial translocation, initiates a cascade of immune activation and inflammatory responses that promotes advanced liver damage

Antibiotics (Basel) 9(11):822 Parsodkar RP, Husain AA, Mudey GD, Singh LR, Kashyap RS (2021) Diagnosis of bacterial meningitis and AMR profile using molecular and immunological techniques