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When the tumor reached 75125 mm 3 , we randomized mice into a vehicle (25% (w/v) hydroxypropyl--cyclodextrin in 10 mmol/L citrate, pH 2) or CB-839 (200 mg/kg) with or without RT (10 Gy/fraction for three consecutive days) treatment groups

Prog Neurobiol 131:2164 Laureys G, Clinckers R, Gerlo S, Spooren A, Wilczak N, Kooijman R, Smolders I, Michotte Y, De Keyser J (2010) Astrocytic 2-adrenergic receptors: From physiology to pathology