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It aids in the metabolism of fats and helps reduce blood cholesterol

Because the reaction consumes both nicotinamide and a methyl donor, changes in NNMT expression may influence the availability of metabolites associated with NAD turnover and methylation balance

Reference AOD-9604 Dosing Protocol In addition to its pill form, AOD-9604 is available for research as a lyophilized powder that should be reconstituted with bacteriostatic water and administered subcutaneously

Combined NNMT inhibition and lean-diet substitution improves adiposity and body-composition endpoints in DIO mice

According to an article about cobalamin deficiency in Tufts Universitys catnip newsletter, people with cobalamin deficiency also experience changes with intestinal permeability and absorptive function