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10.3390/cells13181574 15 CourtneyR.LandrethG

The reason is entirely about gastrointestinal tolerability nausea, diarrhea, and vomiting were clearly dose-dependent and concentrated in the weeks right after each step-up

27,28 Additional advantages of PHIs include ease of administration (oral dosing, especially advantageous in patients not on dialysis or who are on home hemodialysis), cheaper manufacturing with less stringent transportation logistics (ESAs need to be kept refrigerated), 55 and less immunogenicity (a concern with ESAs), given that they are not protein-based

Mossmann, D., Park, S

Symptoms of High B12 Levels in Blood: UK Guide Symptoms of high B12 levels in blood are rarely caused by the elevated vitamin itself

2,21 Interestingly, other macrophages in atherosclerotic plaques take on the role of resolving inflammation