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Ihara M, Kohara N, Urano F, Ichinose H, Takao S, Nishida T, et al

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51 Adjustment for multiple comparisons over time was performed using the quantile of the confidence bands

If you properly store the powder, it will retain its efficacy for quite some time

1,3 References: 1

The apparent lack of a direct effect was noted due to the in vitro environment not mimicking the inherent environment of a tendon in vivo