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While compounds such as bitopertin, BI 425809, and SSR103800 have demonstrated potential in early-stage clinical and preclinical studies, translating these findings into viable treatments remains complex, necessitating further in-depth investigations (Javitt 2012)

Conversely, the targeted activation of key transcription factors like SIAN2 or SIMYB75 using CRISPR activation (CRISPRa) systems or traditional transgenesis has successfully engineered tomatoes with dramatically enhanced anthocyanin accumulation, turning the fruit purple and boosting its antioxidant capacity

Cobalamin and haptocorrin in human milk and cobalamin-related variables in mother and child: A 9-mo longitudinal study

Based on the enzyme kinetic theory, the catalytic activity of CDs was further studied with TMB as a substrate

Structural and functional investigation of bacillithiol disulfide reductases

iTaq universal SYBR Green supermix (Bio-Rad, #1725124) was used for the reaction in a total volume of 12 l (6 l PCR supermix, 1 l cDNA, 1 l primer, 4 l H 2 O)