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Gastroenterology (2017) 153(2):4209

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The first vaccine an individual receives induces a strong primary immune response that shapes responses to subsequent infection and vaccination, an effect known as imprinting, said senior author Michael S

As previously demonstrated, the in vivo administration of N-acetylcysteine attenuates acute TNBS-induced colitis in rats through increased mucosal GSH levels, reducing the extent of intestinal mucosal injury and TNBS-induced ROS overgeneration (127)

Therefore, it's crucial to carefully consider the findings from the reviewed trials in managing RP patients who meet these exclusion criteria

Zhang X, Piano I, Messina A, DAntongiovanni V, Cr F, Provenzano G, et al