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29 Both acute and chronic stress signaling via hormones and neurotransmitters can increase thrombosis risk by increasing platelet numbers, reactivity, and aggregation, disrupting normal vascular function, up-regulating the clotting cascade, and altering fibrinolysis mechanisms

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Shaham O, Wei R, Wang TJ, Ricciardi C, Lewis GD, Vasan RS, Carr SA, Thadhani R, Gerszten RE, Mootha VK (2008) Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity

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For virotherapy applications, incorporation of cancer-targeting peptides into the HI loop of the adenoviral fibre knob, the capsid protein that interacts with the native adenoviral receptor coxsackie adenovirus receptor (CAR) for cell entry, is an opportune targeting strategy for developing high-affinity, retargeted HAdV vectors [7]