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In theory, giving an mRNA vaccine after one that uses a modified virus to deliver genetic material from the SARS-CoV-2 virus as the J&J vaccine does might provide broader protection

Peng Y, Felce SL, Dong D, Penkava F, Mentzer AJ, Yao X, et al

As shown by connected scatterplot in Figure 3 (top-left), the Sucrosomial B12 formulation rapidly raised circulatory vitamin B12 levels above the deficiency threshold, exceeding 300 pg/mL (borderline level) within 24 h (day 1)