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Experimental methods used in this study A random fresh blood sample collected in EDTA tube was obtained from Hamad Medical Corporation (HMC), Doha, Qatar

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Methods: A total of 358 patients with BCLC-B HCC treated with Atezo/Bev (n=177) or LEN (n=181) as first-line systemic therapy were included

qPCR was performed on a QuantStudio 3 System (A28566, Thermo Fisher Scientific) using 0.5 g of cDNA, gene-specific TaqMan primers (see list below), and TaqMan Fast Universal PCR Master Mix (43-660-73, Thermo Fisher Scientific)

Refs, References

When reactive oxygen species threaten your cells, glutathione steps in and neutralizes them, helping to manage oxidative stress