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The addition of testosterone can exacerbate low testosterone levels post-cycle while increasing the risk of gynecomastia and water retention

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Symptoms may include: Shortness of breath Red, flushed skin Headaches Rapid weight gain, polycythemia (increased red cell mass), hypokalemia, CHF, pulmonary edema, and vascular thrombosis are mostly observed in therapeutic contexts where vitamin B12 is administered aggressively or over extended periods

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In 2019 it was estimated that the annual medical cost of obesity in the United States was nearly $173 billion dollars and is estimated to exceed this now