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Ratio of bcl-xshort to bcl-xlong is different in good- and poor-prognosis subsets of acute myeloid leukemia

48 The human GSTP1 gene exists as two functionally different variants, with both variants having documented nucleotide transitions from isoleucine to valine at codon 105 (AG) and alanine to Val at 114 (CT)

However, compared with humans, the ratio of the oral dose to the serum concentration seems to be higher in rats than in humans, making it difficult to directly apply relevant studies to humans (Meftah et al., 2021)