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Fatigue may indicate other medical issues requiring investigation, such as anemia, thyroid dysfunction, vitamin deficiencies, or inadequate glycemic control

But this could also be seen as evidence of the contrary since bromantane has effects that are distinctly different from amantadine and memantine

This effect was more pronounced when m 5 C was located in the 5UTR-CDS and m 1 was restricted to the 3UTR, rather than when m 5 C was located only in the CDS and m 1 in the UTRs [255]