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Description

Autophagy induction by trehalose: molecular mechanisms and therapeutic impacts

J Crohns Colitis 2014

9 , BC25c27 (2015)

These technologies may balance the efficacy and risk through targeting selection (single target/multiple targets, structurally similar targets, undruggable targets, active/non-active sites on targets, protein/PPI), the mode of action on targets (clearance, inhibition, or activation), and the duration and intensity of drug targets