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J Natl Cancer Inst 2005

221 Indeed, HDAC inhibitors such as Vorinostat and valproic acid have shown promising results in solid tumors, especially given in combination with chemotherapeutic agents

Hyperhomocysteinemia decreases GSH peroxidase activity leading to the prevalence of GSSG on GSH with the GSH/GSSG impaired ratio causing some common cardiovascular and neurodegenerative disorders (159)