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Brookes, PhD Allyssa Abel , University of Rochester Mentor: Keith Nerke, PhD Title: Adaptive Stress Regulation of Carbonic Anhydrase 6 in Mouse Neuronal Cell Culture Models Allyssa Abel, Teresa Sherman, Jonathan Malecki,Tori Matthews and Keith Nehrke, PhD Molly Austen , University of Rochester Mentor: Keith Nerke, PhD Title: Mitochondrial UPR and Ca2+ Signaling in C

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Once treatment with iron is started, it is important to repeat a CBC and iron panel in 2-3 months to assess response to treatment

Nrf2 mitigates RANKL and M-CSF induced osteoclast differentiation via ROS-dependent mechanisms

Early symptoms are mild and often go undetected until the disease progresses, at which point management of symptoms becomes the primary standard of care