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Description

In a recently reported phase II/III clinical trial (NCT00444613) on the safety and efficacy of intramuscular ultra-high-dose methylcobalamin in ALS patients, primary endpoints of survival and ALSFRS-R change both failed to show a difference between methylcobalamin (25 and 50 mg) and placebo groups

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Carnitine, Methionine, Thiamine

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Biodistribution Cy 5.5-labeled ZFPG NPs were injected into the tail vein of PC-3 tumor-bearing male nude mice, and fluorescence imaging was performed on mice in the Control (PBS), ZFPG, and ZFPG + MF group at different time points through the IVIS Spectrum system (PerkinElmer), respectively

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This review provides a comprehensive analysis of ferroptosis, focusing on its molecular underpinnings, regulatory networks, and opportunities for therapeutic modulation

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Does your mind feel foggy all day long, no matter how many cups of coffee you have

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