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Further, the ratio of oxidized to reduced glutathione (GSSG/GSH), oxidized glutathione (GSSG), and reduced glutathione (GSH) were significantly higher in the tumor than the surrounding muscle tissue, suggesting increased oxidative stress and the capacity to defend against oxidative stress (Fig

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Figure 2 Interestingly, IL-17A/IL-17A receptor signaling can promote adipogenic transdifferentiation of myoblast cells via activation of the main adipogenic transcription factor PPAR (142)

BSO has also been used in human clinical trials for cancer, where it caused low grade toxicity 30 , suggesting it is not highly cytotoxic

CGRP, calcitonin gene-related peptide

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