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10.1038/s41564-020-0723-z 39 SongY.ZhouZ.GuJ.YangJ.DengJ

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In contrast, in situ cancer vaccines leverage the entire tumor antigen repertoire from the outset, enabling rapid, broad, and dynamically expanding polyclonal T-cell responses, whereas personalized vaccines deliver delayed but precisely targeted responses against selected neoantigens

Sguigna, MD MS & Immune Disorders Chimeric Antigen Receptor T-Cell Therapy for Progressive Multiple Sclerosis: Rationale, Evidence, and Therapeutic Potential Sarah Conway, MD

31 Tripartite motif containing protein 37 (TRIM37) has been reported as an oncogenic histone H2A ubiquitin ligase that is overexpressed in a portion of breast cancers