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doi: 10.3389/fphar.2014.00260 Received 09 July 2014 Accepted 08 November 2014 Published 27 November 2014 Volume 5 - 2014 Edited by Alfonso Pompella, Universit di Pisa, Italy Reviewed by Salvatore Salomone, Catania University, Italy

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However, when Hg 2+ is introduced into the reaction system containing MnFeO oxide, TMB, and Cys, Hg 2+ , due to its high affinity for Cys, binds to Cys to form a stable HgS bond