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Minoxidil works best when hair loss is recent (within 5 years), occurs in younger adults, and affects areas where follicles have not extensively miniaturized

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The TgAPParc mouse model, which carries the E693G mutation (APP695) under the control of the murine Thy1.2 promoter, exhibited 3- to 7-fold higher mutant human APP expression compared to endogenous mouse APP

2d), but dramatic depletion of UMP, UDP and UTP after 24 h of 5FU treatment (Fig