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10.3892/ijmm.2019.4188 233 ZhangH

Proc Natl Acad Sci USA 102: 1554515550 Tabata S, Yamamoto M, Goto H, Hirayama A, Ohishi M, Kuramoto T, Mitsuhashi A, Ikeda R, Haraguchi M, Kawahara K et al (2018) Thymidine catabolism promotes NADPH oxidasederived reactive oxygen species (ROS) signalling in KB and yumoto cells

Specifically, phosphorylation of Ser5 and Ser7 in the CTD was reduced upon CDK7 inhibition 84,85,86

Only vitamin E supplementation significantly increased the overall rate of improvement in histological abnormalities that characterize MASH on liver biopsies (i.e., hepatocellular ballooning, steatosis, and lobular inflammation) (98)

AMP-activated protein kinase signaling in metabolic regulation

Safety, tolerability, and pharmacodynamics of AZD3366 (optimized human CD39L3 apyrase) alone and in combination with ticagrelor and acetylsalicylic acid: a phase 1, randomized, placebo-controlled study