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Figure 1 Figure 2 Although recent advances in RA metabolism research have yielded significant insights into these pathogenic mechanisms, there are considerable challenges in translating this knowledge into effective metabolic pathway-targeted therapies

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Loso MR, Garizi N, Hegde VB, Hunter JE, Sparks TC

Perumpail BJ, Li AA, John N et al (2018) The role of vitamin E in the treatment of NAFLD

MAK071) and a lactate assay kit (Sigma-Aldrich, Cat

The use of reverse pharmacology on traditional MPs and integrating network pharmacology to understand complex biological interactions is strongly recommended for advancing drug discovery today