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Akkaya, M

doi: 10.1016/S0162-0134(02)00511-1 600 MladnkaPMackovKFilipskTZatloukalovLJahodLBovicelliPet al

Enzymes that catalyze antioxidant reactions: Reduced glutathione (G-SH), a tripeptide-thiol (-glutamylcysteinylglycine) present in most cells, can chemically detoxify H 2 O 2 (Figure 13.5B)

Increased apoD and apoA-IV help counteract the chemical modification of high-density lipoprotein (HDL) by advanced glycation end products (AGEs) and carbamylation, which contributes to the loss of function of HDL in maturing DKD, thereby delaying DKD (192)