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Given the extensive reprogramming of the AR cistrome towards non-canonical targets during progression to mCRPC 34,35 , these results suggest that NSD2 loss facilitates a shift towards a more canonical AR program

Sankpal et al

Now that shes using tirzepatide, she said, she feels peace without the food noise and notes that part of what stopped it is a side effect of the medication: She physically feels kind of always bloated and not hungry. Summer Kessel, who has been using tirzepatide for over two years, said she was a bottomless pit who always felt hungry