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When she wasn't losing weight, she supplemented her treatment with semaglutide

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found that mutations in the PNPO genes R225H/C, D33V, and R116Q/P significantly reduced PNPO activity and increased the likelihood of PN-responsive epilepsy [35]

Ultimately, implementation of immune-augmenting nutritional supplements within breast cancer care may require personalized approaches taking into consideration tumour subtype, underlying immunologic competency/deficiency, previous treatments received, microbiome profile and comorbid autoimmunity as well as multidisciplinary teamwork to translate promising immunobiologic signals into safe and empirically defined adjuncts to conventional anticancer immunity that are additive rather than counterproductive to patient health (197)

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Patient samples were obtained under SingHealth CIRB Ref: 2004/407/F