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*Correspondence: Raffaela Maione, [email protected] ORCID: Raffaela Maione, orcid.org/0009-0002-0491-2018 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Intrahepatic GSH can detoxify NAPQI generated from APAP by the conjugation, but there was no significant difference in intrahepatic GSH level between unchallenged WT and IL-1ra KO mice