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Excess visceral fat leads to increased production of pro-inflammatory cytokines, including TNF-, IL-6, and IL-17, as well as the following adipokines: leptin, visfatin, and resistin, which exacerbate inflammation (205)

doi: 10.1038/s41380-018-0017-5 182 PanAKeumNOkerekeOISunQKivimakiMRubinRRet al

**** Thyroid function disturbances **** Potential for kidney dysfunction , leading even to kidney failure Severe abdominal pain Incorrect technique of injection (especially by an untrained person) can result in sepsis, HIV, & other infections Conclusions There is no published data for either the safety or efficacy of glutathione injections for skin lightening.There is very little evidence that establishes either the safety or efficacy of glutathione injections for skin lightening

Microneedling Microneedling creates controlled micro-injuries to stimulate natural repair processes

Although these findings appear promising, the utility of intravenous NAC repletion as a therapeutic strategy in PD is greatly limited by invasiveness and inconvenience of intravenous delivery

(Shanghai) 48 , 7581 (2016)