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The IC 50 values of the synthesized compounds deviated significantly from that belonging to the reference compounds, with the 5-SH analogues 32 and 34 as the most active

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BPC-157 is believed to interact with the nitric oxide (NO) system, angiogenic growth factors, and cellular signaling pathways like FAK-paxillin and VEGF, which are involved in cell migration, cytoskeletal reorganization, and vascular modulation