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Senescence was induced with 100 nM 4-OHT for 7 days, while non-senescent cell controls were obtained by treating cells with DMSO

The resulting structural and functional impairments in neuronal integrity contribute to cognitive deficits, mood dysregulation, and other neuropsychiatric symptoms, thereby reinforcing a self-perpetuating cycle of neuroimmune dysregulation

By employing these methods, researchers can gain insights into how modifying gene activity affects seizure control and neuronal function, providing valuable information for developing targeted therapies

Crit Rev Eukaryot Gene Expr

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N-Acetyl-L-Cysteine (NAC)