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Science 257:14961502 Holmgren A, Sengupta R (2010) The use of thiols by ribonucleotide reductase

To overcome challenges such as biosafety, off-target effects, and clinical translatability, strategies successfully explored in other diseases, such as biodegradable or organicinorganic hybrid nanozymes, pH-responsive targeting designs, erythrocyte membrane coatings, and ROS-responsive carriers, may be adapted to enhance tissue specificity and safety in IMID treatment

In this work, we identify a conserved set of genes activated by mitochondrial translation inhibition and establish C32E8.9 as essential for the resulting healthspan and lifespan extension in C

Glutathione is an antioxidant your body makes itself and keeps in nearly every cell, where it neutralizes oxidative stress and supports detoxification

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This synthetic peptide consists of the C-terminal fragment (amino acids 176-191) of human growth hormone with an additional tyrosine residue at the N-terminus, designed to retain the lipolytic properties of growth hormone while avoiding its growth-promoting effects