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The new approval for Retevmo, which was previously authorized to treat patients 12 and older with RET-positive thyroid cancers, is based on a single-arm study that showed an overall response rate of 48%, with a median duration of response not reached after 12 months of follow-up

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Several studies revealed beneficial effects of alogliptin in discrete models

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These side effects, including changes in diastolic blood pressure, are typically dose-dependent, meaning they may be more pronounced with higher doses