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Once activated by exogenous stimuli, GPCRs primarily employ heterotrimeric G-proteins and arrestins as transducers to produce second messengers and further initiate the downstream signaling, resulting in promiscuous signaling profiles within cells

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S., Moszczynska, A., Mattina, K., Ang, L.-C., Boileau, I., Furukawa, Y., Sailasuta, N., & Kish, S

, kilobase level events, and not smaller insertion-deletion polymorphisms) that are common in human populations are depleted for coding sequences [5]

Mahon KL, Qu W, Devaney J, Paul C, Castillo L, Wykes RJ, et al

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