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Reactive oxygen and nitrogen species during viral infections

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Malondialdehyde (MDA) and 4-hydroxynonenal (HNE) (Figure 1), end products of lipid peroxidation, are discharged from destroyed hepatocytes into the space of Disse (Figure 2)

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and acetyl-L-carnitine (ALCAR) is the brain-penetrant form studied for mood and cognition (Veronese 2018, PMID 29076953)

The different cardiac expression of the type 2 iodothyronine deiodinase gene between human and rat is related to the differential response of the Dio2 genes to Nkx-2.5 and GATA-4 transcription factors