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10.1021/acs.jafc.6b04835 16 BehrensM.RedelU.BlankK.MeyerhofW

Mechanisms of MHC-I downregulation and role in immunotherapy response

Given the involvement of various cell death modalities, such as necroptosis, autophagy, and apoptosis, in thyroid cancer treatment, it would be highly beneficial to explore the effects of combination therapies that target distinct cell death pathways

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Our observations support the growing evidence that CD19-directed CAR T-cell therapy is particularly well tolerated in autoimmune diseases and highlight that disease biology is a key determinant of CAR T-cell expansion, toxicity, and immune recovery