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The concurrent use of ketorolac tromethamine and therapy that affects hemostasis, including prophylactic low-dose heparin (2500 to 5000 units q12h), warfarin and dextrans have not been studied extensively, but may also be associated with an increased risk of bleeding

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Namely, without upgrading, one sole episcleral vein function could not perform the whole function of aqueous fluid drainage [116,117,118,119,120,121]

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