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Immune checkpoint inhibitors (ICIs) have dramatically improved survival in a subset of patients by reactivating exhausted T cells [1]

Additionally, the mutant huntingtin protein can impair the function of the transcription factor PGC-1, which is crucial for the regulation of antioxidant defenses and mitochondrial biogenesis

L-Glutathione Reduced

however, when it is overexpressed it can contribute to pathogenic manifestations

doi: 10.1242/jcs.126128 9 BraunerS.ZhouW.BacklinC.GreenT

Flavonoids exhibit various biological activities, including anti-inflammatory, anticancer, antiviral, antidiabetic, anti-cardiovascular, and antioxidant activity [188,189,190]