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Bieging KT, Fish K, Bondada S, Longnecker R

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Research consistently supports intakes of 0.7 to 1.0 grams of protein per pound of body weight daily for individuals in a caloric deficit

Future therapeutic approaches may involve: Microbiome-targeted therapies Gut-derived peptide treatments Personalized nutrition based on microbial composition These emerging strategies reflect a broader shift in metabolic medicine toward addressing root causes rather than simply managing symptoms

The FDA has cited concerns over the lack of large-scale, randomized, placebo-controlled human trials demonstrating its safety and efficacy